The fruits of mangosteen are used in traditional medicine in Southeast Asia to treat skin infections, wounds, and diarrhea. Laboratory studies have shown that compounds present in mangosteen fruit are effective against bacterial and fungal infections and can reduce inflammation. Other studies have shown that mangosteen can inhibit the growth of various types of cancer cells. There is also evidence that some compounds in mangosteen act as free-radical scavengers to prevent damage by low density lipoprotein (LDL), more commonly known as bad cholesterol.
Small clinical studies suggest benefits of mangosteen-containing products as adjuncts in periodontal treatment; controlling halitosis; and in the treatment of chronic periodontitis.  Mangosteen extracts were also found useful for weight management. Confirmatory studies are needed.